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Vitamin C is involved in collagen metabolism and integrity, so its use prevents ROS-induced collagen injury to chorioamniotic membranes, reducing PPROM, as shown in different studies [15,86,87,88,94,95]

Inhibition of glutaminolysis ameliorates lupus by regulating T and B cell subsets and downregulating the mTOR/P70S6K/4EBP1 and NLRP3/caspase-1/IL-1beta pathways in MRL/lpr mice

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Additionally, absorption issues due to gastrointestinal (GI) problems and food sensitivities may limit the availability of selenium from food sources

Individual responses vary based on genetics, baseline skin tone, environmental factors, and overall health status, which explains why some people report noticeable results while others see minimal changes